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Friday, May 15, 2020 | History

1 edition of Molecular structure of nucleic acids. found in the catalog.

Molecular structure of nucleic acids.

Molecular structure of nucleic acids.

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Published by [s.n.] in [U.K.] .
Written in English

    Subjects:
  • Nucleic acids.,
  • DNA.

  • Edition Notes

    Offprint from Nature, v.171, p. 737, April 25, 1953.

    ContributionsWatson, James D. 1928-
    The Physical Object
    Pagination13, [1]p. :
    Number of Pages13
    ID Numbers
    Open LibraryOL16183056M

      The determination in of the structure of deoxyribonucleic acid (DNA), with its two entwined helices and paired organic bases, was a tour de force in X-ray crystallography. But more. THE FIRST ANNOUNCEMENT OF THE DISCOVERY OF THE STRUCTURE OF DNA which revolutionised biochemistry and the life sciences. ‘Molecular Structure of Nucleic Acids’ and ‘Genetical Implications of the Structure of Deoxyribonucleic Acid’ were published in Nature, January-June , volume , pp , this copy bound in brown pebbled cloth, a near fine copy.

    Nucleic acids are the biopolymers, or small biomolecules, essential to all known forms of term nucleic acid is the overall name for DNA and RNA. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous the sugar is a compound ribose, the polymer is RNA (ribonucleic acid); if the sugar is derived. We wish to suggest a structure for the salt of deoxyribose nucleic acid D.N.A.. This structure has novel features which are of considerable biological interest It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material. First separate edition offprint of the three papers announcing the discovery of.

    Carbohydrates illustrate the importance of subtle differences in covalent bonds in generating molecules with different biological activities. However, several types of noncovalent bonds are critical in maintaining the three-dimensional structures of large molecules such as proteins and nucleic acids (see Figure b).Noncovalent bonds also enable one large molecule to bind specifically but. Nucleic acids are polynucleotide chains in which ribonucleotides and deoxyribonucleotides are the monomeric units (Section ) of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) tides are composed of three component parts: a heterocyclic ring structure, a pentose sugar and a phosphate group, each of which contributes to the chemistry of the unit.


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Molecular structure of nucleic acids Download PDF EPUB FB2

The Watson & Crick paper ("Molecular Structure of Nucleic Acids") "records the discovery of the molecular structure of deoxyribonucleic acid (DNA), the main component of chromosomes and the material that transfers genetic characteristics in all life forms.

Publication of this paper initiated the science of molecular biology. Polymerization of Nucleotides Forms Nucleic Acids. DNAand RNAeach consists of only four different nucleotides. All nucleotideshave a common structure: a phosphategroup linked by aphosphoester bond to a pentose(a five-carbon sugar molecule)that in turn is linked to an organic base(Figure a).Cited by: 5.

The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved.

Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA/5(6). The Watson & Crick paper ("Molecular Structure of Nucleic Acids") "records the discovery of the molecular structure of deoxyribonucleic acid (DNA), the main component of chromosomes and the material that transfers genetic characteristics in all life forms.

Publication of this paper initiated the science of molecular biology. : Molecular Structure of Nucleic Acids: First separate edition (offprint) of the three papers announcing the discovery of the structure of DNA, one of the. : Molecular structure of nucleic acids. A structure for deoxyribose nucleic acid: The Double Helix The "Three-Paper" Offprint, Signed by Five of its Authors Watson, James D.

() & Crick, Francis H. Molecular structure of nucleic acids. A structure for deoxyribose nucleic acid. With: Wilkins, Maurice (); Stokes, A. R.; & Wilson, H. Molecular Price Range: $1, - $95, Nucleic Acids Book.

A free online book on the chemistry and biology of nucleic acids, written by Prof. Tom Brown and Dr Tom Brown (Jnr). The book is ideal for chemistry and biology students and also provides practical information for researchers working in the lab. Nucleic Acids Nucleic acids are key macromolecules in the continuity of life.

They carry the genetic blueprint of a cell and carry instructions for the functioning of the cell. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material found in all living organisms, ranging from. In AprilJames Watson and Francis Crick published "Molecular Structure of Nucleic Acids: A Structure of Deoxyribose Nucleic Acid" or "A Structure for Deoxyribose Nucleic Acid," in the journal the article, Watson and Crick propose a novel structure for deoxyribonucleic acid or DNA.

InOswald T. Avery and his group at Rockefeller University in New York City, New York. Basic structure Nucleic acids are polynucleotides—that is, long chainlike molecules composed of a series of nearly identical building blocks called nucleotides.

Each nucleotide consists of a nitrogen-containing aromatic base attached to a pentose (five-carbon) sugar, which. The sequence of nucleotides in a nucleic acid defines the primary structure of the molecule.

RNA is a single-chain nucleic acid, whereas DNA possesses two nucleic-acid chains intertwined in a secondary structure called a double helix. London: Macmillan, First edition of Watson & Crick’s paper which “records the discovery of the molecular structure of deoxyribonucleic acid DNA, the main component of chromosomes and the material that transfers genetic characteristics in all life forms.

Publication of this paper initiated the science of molecular biology. Forty years after Watson and Crick's discovery, so much of. Molecular structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid was a paper published by James D. Watson and Francis Crick in the scientific journal Nature in its th volume on page (dated Ap ).

It was the first publication which described the discovery of the double helix structure of DNA. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid" was the first article published to describe the discovery of the double helix structure of DNA, using X-ray diffraction and the mathematics of a helix transform.

T. Ming Chu Professor (Biochemistry and Molecular Biology) at The Pennsylvania State University. Table of contents. Contributors. DNA and RNA are both nucleic acids, which are the polymeric acids isolated from the nucleus of cells. DNA and RNA can be represented as simple strings of letters, where each letter corresponds to a particular nucleotide, the monomeric component of the nucleic.

The nucleic acids, DNA and RNA, may be thought of as the information molecules of the cell. In this section, we will examine the structures of DNA and RNA, and how these structures are related to the functions these molecules perform. “Molecular structure of nucleic acids.

A structure of deoxyribose nucleic acid.” Offprint from: Nature Vol. (Ap ) London, 13, (1) pp. Original self-wrappers. An excellent example.

By: Hernandez, Victoria Keywords: DNA, A-Form [2] DNA structure [3] Watson-Crick model [4] In AprilJames Watson [5] and Francis Crick [6] published "Molecular Structure of Nucleic Acids: A Structure of Deoxyribose Nucleic Acid" or "A Structure for Deoxyribose Nucleic Acid," in the journal Nature.

In the article, Watson and Crick propose. The book is a rich source of information about DNA and RNA and will help the reader appreciate the wide panorama of experimental and computational research directions.

This volume should be in complete collections of books on computational chemistry or nucleic acids."--Journal of Medicinal Chemistry "Proceedings of the April : $ B.S. Guttman, in Encyclopedia of Genetics, All nucleic acids have the same fundamental structure: The nucleotide monomers are joined to one another through phosphodiester linkages between the sugars, thus forming a backbone of alternating sugars and phosphates with the bases emerging to the side (see illustration).

The phosphodiester linkages always connect the 5′-carbon of one sugar. The Watson & Crick paper ("Molecular Structure of Nucleic Acids") “records the discovery of the molecular structure of deoxyribonucleic acid (DNA), the main component of chromosomes and the material that transfers genetic characteristics in all life forms.

Publication of this paper initiated the science of molecular biology.Nucleic Acid Structure and Recognition will therefore equip readers with a good understanding of all the important aspects of this major field.

The Nucleic Acid Database (NDB) crystallographic and NMR structures for the nucleic acid structures described in the book are freely available through the Nucleic Acid Structure and Recognition by:   A structure for nucleic acid has already been proposed by Pauling and Corey1. They kindly made their manuscript available to us in advance of by: